博士後期課程3年の松﨑英章さんの原著論文が受理されました。
 
著者名：Hideaki Matsuzaki, Hiro Kishimoto, Yu Nofuji, Tao Chen, Kenji Narazaki
論文名：Predictive Ability of the Total Score of the Kihon Checklist for the Incidence of Functional Disability in Older Japanese Adults: An 8-Year Prospective Study
雑誌名：Geriatrics & Gerontology International

Abstract：
Aim: To investigate the association between the total score of the Kihon Checklist (t-KCL score) and functional disability over an 8-year follow-up period, and to examine whether the t-KCL score in the basic model with risk factors contributes to the incremental predictive ability for functional disability among older adults.
Methods: We followed 2,209 older adults aged ≥65 years without functional disability at a baseline. The t-KCL score was determined using a baseline survey questionnaire. Functional disability was defined based on information of long-term care certifications. The association between the t-KCL score and functional disability was examined using the Cox proportional hazards model. The incremental predictive ability of the t-KCL score for functional disability was evaluated by the difference of C-statistic, category-free net reclassification improvement (NRI), and integrated discrimination improvement (IDI).
Results: The median follow-up period was 7.8 years, and 557 participants developed functional disability. The adjusted hazard ratio (95% confidence interval [CI]) of functional disability for a 1-point increase of the t-KCL score was 1.08 (1.06–1.10). Adding the t-KCL score to the basic model significantly improved the C-statistic (95% CI) from 0.747 (0.728–0.768) to 0.760 (0.741–0.781). When the t-KCL score was added to a basic model, the NRI and IDI were 0.187 (95% CI: 0.095–0.287) and 0.020 (95% CI: 0.012–0.027), respectively.
Conclusions: The t-KCL score had an independent positive association with functional disability over an 8-year follow-up. Furthermore, adding the t-KCL score to the basic model improved the predictive ability for functional disability.