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2022.07.21
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論文受理
共同研究者の齊藤貴文先生（令和健康大学・講師）の論文がPain Reportsに受理されました。
Title: Independent and combined associations of depressive symptoms and sleep disturbance with chronic pain in community-dwelling older adults
Authors: Takafumi Saito, Tao Chen, Harukaze Yatsugi, Tianshu Chu, Xin Liu, Hiro Kishimoto
Abstract
Introduction: There is limited evidence regarding whether depressive symptoms and sleep disturbance are independently or synergistically associated with chronic pain.
Objectives: We investigated the independent and combined associations of depressive symptoms and sleep disturbance with chronic pain and its severity (and the additive interactions) in community-dwelling older adults.
Methods: This cross-sectional study analyzed the data of 1,374 individuals who were 65−75 years old, not in need of long-term care, and completed questionnaires assessing sociodemographic factors, depressive symptoms, sleep disturbance and chronic pain. The severity of chronic pain was assessed based on pain intensity, pain distribution, and pain type. The participants' status of depressive symptoms and sleep disturbance were categorized in the following four groups: neither-condition, depressive symptoms alone, sleep disturbance alone, and both-conditions.
Results: Among the 1,374 participants, 849 (61.8%) had chronic pain. The multivariable adjusted odds ratios and 95% confidence intervals of the presence of chronic pain in those with depressive symptoms alone, sleep disturbance alone, and both-conditions were 1.40 (0.97–2.03), 1.98 (1.41–2.78), and 2.12 (1.39–2.23), respectively compared to the neither-condition group. Similar associations were observed for severe chronic pain. However, there were no significant additive interactions. In addition, only sleep disturbance was significantly associated with chronic pain, after adjusting for depressive symptoms.
Conclusions: Our analyses did not reveal a synergistic effect of depressive symptoms and sleep disturbance on chronic pain and its severity, suggesting that most of the effects of depressive symptoms on chronic pain may be mediated by sleep disturbance.
Title: Independent and combined associations of depressive symptoms and sleep disturbance with chronic pain in community-dwelling older adults
Authors: Takafumi Saito, Tao Chen, Harukaze Yatsugi, Tianshu Chu, Xin Liu, Hiro Kishimoto
Abstract
Introduction: There is limited evidence regarding whether depressive symptoms and sleep disturbance are independently or synergistically associated with chronic pain.
Objectives: We investigated the independent and combined associations of depressive symptoms and sleep disturbance with chronic pain and its severity (and the additive interactions) in community-dwelling older adults.
Methods: This cross-sectional study analyzed the data of 1,374 individuals who were 65−75 years old, not in need of long-term care, and completed questionnaires assessing sociodemographic factors, depressive symptoms, sleep disturbance and chronic pain. The severity of chronic pain was assessed based on pain intensity, pain distribution, and pain type. The participants' status of depressive symptoms and sleep disturbance were categorized in the following four groups: neither-condition, depressive symptoms alone, sleep disturbance alone, and both-conditions.
Results: Among the 1,374 participants, 849 (61.8%) had chronic pain. The multivariable adjusted odds ratios and 95% confidence intervals of the presence of chronic pain in those with depressive symptoms alone, sleep disturbance alone, and both-conditions were 1.40 (0.97–2.03), 1.98 (1.41–2.78), and 2.12 (1.39–2.23), respectively compared to the neither-condition group. Similar associations were observed for severe chronic pain. However, there were no significant additive interactions. In addition, only sleep disturbance was significantly associated with chronic pain, after adjusting for depressive symptoms.
Conclusions: Our analyses did not reveal a synergistic effect of depressive symptoms and sleep disturbance on chronic pain and its severity, suggesting that most of the effects of depressive symptoms on chronic pain may be mediated by sleep disturbance.