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Enhancement of Aggregate Formation Through Aromatic Compound Adsorption in Elastin-like Peptide (FPGVG)5 Analogs
Biomacromolecules 2023, 24, 11, 5265-5276 (Article)
Subscribed Publication Date (Web):October 22, 2023
DOI: 10.1021/acs.biomac.3c00779

薬史を題材とした学部生向けの英語ライティング教材の開発
薬史学雑誌 Vo;. 58(2), (2023) 掲載決定



Ugi Adducts as Novel Anti-austerity Agents against PANC-1 Human Pancreatic Cancer Cell Line: A Rapid Synthetic Approach
Biological and Pharmaceutical Bulletin 46(10), 1412, (2023)
https://doi.org/10.1248/bpb.b23-00224


Determining the Sequence Dependency of Self-Assembly of Elastin-Like Peptides Using Short Peptide Analogues with Shuffled Repetitive Sequences
Biochemistry, 62(17), 2559 (2023)
https://doi.org/10.1021/acs.biochem.3c00146

Development of the efficient preparation method for thermoresponsive elastin-like peptides using liquid-phase synthesis combined with fragment condensation strategy
Journal of Peptide Science, June (2023).
https://doi.org/10.1002/psc.3528

High cytotoxicity of a degraded TBBPA, dibromobisphenol A, through apoptotic and necrosis pathways
Heliyon, Volume 9, Issue 1, e13003, January (2023).
https://doi.org/10.1016/j.heliyon.2023.e13003

Development of truncated elastin-like peptide analogues with improved temperature-response and self-assembling properties
Scientific Reports, volume12, Article number: 19414 (2022).
https://doi.org/10.1038/s41598-022-23940-0


Branched short elastin-like peptides with temperature responsiveness obtained by EDTA-mediat
ed multimerization
Journal of Peptide Science, e3449, (2022)



Product hybrids by the Ugi reaction in complex media conatining  
Scientific Reports, volume12, Article number: 15568 (2022).
https://doi.org/10.1038/s41598-022-19579-6


Flexible customization of the self-assembling abilities of short elastin-like peptide Fn analogs by substituting N-terminal amino acids
Biopolymers, e23521, 2022


Metal ion scavenging activity of elastin-like peptide analogues containing a cadmium ion binding sequence
Scientific Reports, volume12, Article number: 1861 (2022)
https://doi.org/10.1038/s41598-022-05695-w

Direct evidence of edge-to-face CH/π interaction for PAR-1 thrombin receptor activation
Bioorganic & Medicinal Chemistry, 2021 51, 116498.
https://doi.org/10.1016/j.bmc.2021.116498

Bisphenol A derivatives act as novel coactivator binding inhibitors for estrogen receptor β
J. Biol. Chem., 2021 297(5) 101173.
https://doi.org/10.1016/j.jbc.2021.101173

Simple Regulation of the Self-Assembling Ability by Multimerization of Elastin-Derived Peptide (FPGVG)n Using Nitrilotriacetic Acid as a Building Block
ACS Omega
 2021, 6, 8, 5705–5716
https://doi.org/10.1021/acsomega.0c06140

Bisphenol-C is the strongest bifunctional ERα-agonist and ERβ-antagonist due to magnified halogen bonding
PLOS ONE, 2021, https://doi.org/10.1371/journal.pone.0246583

Mechanistic insights into a DMSO-perturbing inhibitory assay of hyaluronidase
Biochemistry, 2020, 59, 40, 3879–388.
https://doi.org/10.1021/acs.biochem.0c00594

Evaluation of the Influence of Halogenation on the Binding of Bisphenol A to the Estrogen-Related Receptor γ
Chem. Res. Toxicol. 2020, 33, 4, pp889-902. https://doi.org/10.1021/acs.chemrestox.9b00379.

Bisphenol AF: Halogen bonding effect is a major driving force for the dual ERα-agonist and ERβ-antagonist activities
Bioorganic & Medicinal Chemistry, 2020 Feb 1;28(3):115274.

Early identification of promiscuous attributes of aldose reductase inhibitors using a DMSO-perturbation assay
Bioorganic & Medicinal Chemistry Letters, 2020 Jan 15;30(2):126815.

Receptor-binding affinities of bisphenol A and its next-generation analogs for human nuclear receptors
Toxicology and Applied Pharmacology, 8, 15 2019, 377, 114610.

DMSO-Perturbing Assay for Identifying Promiscuous Enzyme Inhibitors
ACS Med. Chem. Lett., 10.1021/acsmedchemlett.9b00093, 2019, 10, 6, pp 923-928, 2019.06

Importance of Receptor Conformations in Docking Calculation-Based Risk Assessment for Endocrine Disruptors against Estrogen Receptor α, ACS Omega, 10.1021/acsomega.9b000, 502019, 4 (4), pp 6620–6629, 2019.04.

Enhancement of self-aggregation properties of linear elastin-derived short peptides by simple cyclization strong self-aggregation properties of cyclo[FPGVG]n, consisting only of natural amino acids, Biomacromolecules, 10.1021/acs.biomac.8b00353, 19, 8, 3201-3211, 2018.02

Stepwise Mechanism of Temperature-Dependent Coacervation of the Elastin-like Peptide Analogue Dimer, (C(WPGVG)3)2, Biochemistry, 10.1021/acs.biochem.7b01144, 57, 10, 1582-1590, 2018.03.

Angiotensin I Converting Enzyme-inhibiting Peptides Purified from Elastase-degraded Elastin Prepared from Pig Aorta, Current Enzyme Inhibition, 10.2174/1573408013666170912113121, 14, 67-74, 2018.03.

Multifunctional biological activities of water extract of housefly larvae (Musca domestica), PharmaNutrition, 10.1016/j.phanu.2017.09.001, 5, 4, 119-126, 2017.12

Investigation of water-soluble elastin as a multifunctional cosmetic material: Moisturizing and whitening effects, JOURNAL OF COSMETIC SCIENCE, 10.1002/psc.2837, 68, 1-13, 2017.01.

Role of individual disulfide bridges in the conformation and activity of spinoxin (α-KTx6.13), a potassium channel toxin from Heterometrus spinifer scorpion venom, Toxicon, 10.1016/j.toxicon.2016.09.013, 122, 31-38, 2016.11.

Active Sites of Spinoxin, a Potassium Channel Scorpion Toxin, Elucidated by Systematic Alanine Scanning, Biochemistry, 10.1021/acs.biochem.6b00139, 55, 21, 2927-2935, 2016.05.

Dimerization effects on coacervation property of an elastin-derived synthetic peptide (FPGVG)5, Journal of Peptide Science, 10.1002/psc.2876, 22, 236-243, 2016.03.

Development of short and highly potent self-assembling elastin-derived pentapeptide repeats containing aromatic amino acid residues, Journal of Peptide Science, 10.1002/psc.2837, 22, 1, 36-42, 2016.01.

Design of Phenylalanine-Containing Elastin-Derived Peptides Exhibiting Highly Potent Self-Assembling Capability , Protein & Peptide Letters, 10.2174/092986652210150821170703, 22, 10, 939-939, 2015.08.

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生体分子化学研究室

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