PublicationsPeer-reviewed Articles

This page lists selected peer-reviewed journal articles published in English. It does not include proceedings papers, extended abstracts, non-peer-reviewed presentations, or reports.

Notation: * = corresponding author; # = equal contribution.

I. Fundamental Neuroscience (Neural Basis)

Research on sensory and cognitive functions (vision, olfaction, emotion, and memory), centered on neural measurements and quantitative data analysis. This line of work also extends to clinical neuroscience, including neurological disorders and neuropathology.

2023: Hideko Noguchi, Sachiko Koyama, Kaoru Yagita, Masahiro Shijo, Kosuke Matsuzono, Hideomi Hamasaki, Tsuyoshi Okamoto, Keita Kai, Shinichi Aishima, Koji Abe, Naokazu Sasagasako, Hiroyuki Honda*: Silence of resident microglia in GPI anchorless prion disease and activation of microglia in Gerstmann-Sträussler-Scheinker disease and sporadic Creutzfeldt-Jakob disease. Journal of Neuropathology & Experimental Neurology 82, 38–48, 2023.
2021: Akinori Takeda*, Emi Yamada, Taira Uehara, Katsuya Ogata, Tsuyoshi Okamoto, Shozo Tobimatsu: Data-point-wise spatiotemporal mapping of human ventral visual areas: Use of spatial frequency/luminance-modulated chromatic faces. NeuroImage 239, 118325, 2021.; Chun Lum Andy Ho, Robert Zimmermann, Juan Daniel Flórez Weidinger, Mario Prsa, Manuel Schottdorf, Sam Merlin, Tsuyoshi Okamoto, Koji Ikezoe, Fabien Pifferi, Fabienne Aujard, Alessandra Angelucci, Fred Wolf, Daniel Huber*: Orientation Preference Maps in Microcebus murinus Reveal Size-Invariant Design Principles in Primate Visual Cortex. Current Biology 31, 733–741, 2021.
2020: Minako Kawaguchi, Kazuhiro Samura*, Yasushi Miyagi, Tsuyoshi Okamoto, Ryo Yamasaki, Nobutaka Sakae, Fumiaki Yoshida, Koji Iihara: The effects of chronic subthalamic stimulation on nonmotor symptoms in advanced Parkinson’s disease, revealed by an online questionnaire program. Acta Neurochirurgica 162, 247–255, 2020.
2019: Hideomi Hamasaki, Hiroyuki Honda, Satoshi O. Suzuki, Masahiro Shijo, Tomoyuki Ohara, Yozo Hatabe, Tsuyoshi Okamoto, Toshiharu Ninomiya, Toru Iwaki: Tauopathy in basal ganglia involvement is exacerbated in a subset of patients with Alzheimer’s disease: The Hisayama study. Alzheimer’s & Dementia: Diagnosis, Assessment and Disease Monitoring 11, 415–423, 2019.; Kazuhiro Samura, Yasushi Miyagi, Minako Kawaguchi, Fumiaki Yoshida, Tsuyoshi Okamoto, Masatou Kawashima: Predictive Factors of Antiparkinsonian Drug Reduction after Subthalamic Stimulation for Parkinson’s Disease. Neurologia medico-chirurgica 59, 331–336, 2019.
2017: Hideomi Hamasaki, Hiroyuki Honda, Tsuyoshi Okamoto, Sachiko Koyama, Satoshi O. Suzuki, Tomoyuki Ohara, Toshiharu Ninomiya, Yutaka Kiyohara, Toru Iwaki: Recent Increases in Hippocampal Tau Pathology in the Aging Japanese Population: The Hisayama Study. Journal of Alzheimer’s Disease 55(2), 613–624, 2017.; Yoshikazu Kikuchi*, Tsuyoshi Okamoto, Katsuya Ogata, Koichi Hagiwara, Toshiro Umezaki, Masamutsu Kenjo, Takashi Nakagawa, Shozo Tobimatsu: Abnormal auditory synchronization in stuttering: A magnetoencephalographic study. Hearing Research 344, 82–89, 2017.; Kaori Tamura, Takaaki Mizuba, Tsuyoshi Okamoto, Mayumi Matsufuji, Sachio Takashima, Keiji Iramina: Evaluation of cognitive function when hearing one’s own name in patients with brain injuries in early developmental stages. Journal of Clinical Neurophysiology 34(3), 254–260, 2017.
2014: Koichi Hagiwara*, Katsuya Ogata, Tsuyoshi Okamoto, Taira Uehara, Naruhito Hironaga, Hiroshi Shigeto, Jun-ichi Kira, Shozo Tobimatsu: Age-related changes across the primary and secondary somatosensory areas: An analysis of neuromagnetic oscillatory activities. Clinical Neurophysiology 125(5), 1021–1029, 2014.; Taira Uehara*, Takao Yamasaki, Tsuyoshi Okamoto, Takahiko Koike, Shigeyuki Kan, Satoru Miyauchi, Jun-ichi Kira, Shozo Tobimatsu: Efficiency of a “small-world” brain network depends on consciousness level: A resting-state fMRI study. Cerebral Cortex 24(6), 1529–1539, 2014.
2012: Horie S, Yamasaki T, Okamoto T, Kan S, Ogata K, Miyauchi S, Tobimatsu S: Distinct role of spatial frequency in dissociative reading of ideograms and phonograms: An fMRI study. NeuroImage 63, 979–988, 2012.; Shizuka Horie, Takao Yamasaki, Tsuyoshi Okamoto, Taisuke Nakashima, Katsuya Ogata, Shozo Tobimatsu: Differential roles of spatial frequency on reading processes for ideograms and phonograms: A high-density ERP study. Neuroscience Research 72(1), 68–75, 2012.
2011: [Representative Paper]
Tsuyoshi Okamoto*, Koji Ikezoe, Hiroshi Tamura, Masataka Watanabe, Kazuyuki Aihara, Ichiro Fujita: Predicted contextual modulation varies with distance from pinwheel centers in the orientation preference map. Scientific Reports 1, 114, 2011.; Yoshikazu Kikuchi, Katsuya Ogata, Toshirou Umesaki, Takashi Yoshiura, Masamutsu Kenjo, Yoji Hirano, Tsuyoshi Okamoto, Shizuo Komune, Shozo Tobimatsu: Spatiotemporal Signatures of an Abnormal Auditory System in Stuttering. NeuroImage 55(3), 891–899, 2011.
2010: [Representative Paper]
Koichi Hagiwara#, Tsuyoshi Okamoto#, Hiroshi Shigeto*, Katsuya Ogata, Yuko Somehara, Takuya Matsushita, Jun-ichi Kira, Shozo Tobimatsu: Oscillatory gamma synchronization binds the primary and secondary somatosensory areas in Humans. NeuroImage 51(1), 412–420, 2010.
2009: Yasushi Miyagi, Tsuyoshi Okamoto, Takato Morioka, Shozo Tobimatsu, Yoshitaka Nakanishi, Kazuyuki Aihara, Kimiaki Hashiguchi, Nobuya Murakami, Fumiaki Yoshida, Kazuhiro Samura, Shinji Nagata, Tomio Sasaki: Spectral Analysis of Field Potential Recordings by Deep Brain Stimulation Electrode for Localization of Subthalamic Nucleus in Patients with Parkinson’s Disease. Stereotactic and Functional Neurosurgery 87(4), 211–218, 2009.; Katsuya Ogata*, Tsuyoshi Okamoto, Takao Yamasaki, Hiroshi Shigeto, Shozo Tobimatsu: Pre-movement gating of somatosensory-evoked potentials by self-initiated movements: The effects of ageing and its implication. Clinical Neurophysiology 120(6), 1143–1148, 2009.
2007: Y. Nakanishi, H. Higaki, T. Takashima, T. Umeno, K. Shimoto, Tsuyoshi Okamoto: Change in Gait by Footwear. Journal of Biomechanical Science and Engineering 2(4), 228–236, 2007.
2004: [Representative Paper]
Tsuyoshi Okamoto*, Masataka Watanabe, Kazuyuki Aihara, Shunsuke Kondo: An Explanation of Contextual Modulation by Short-range Isotropic Connections and Orientation Map Geometry in the Primary Visual Cortex. Biological Cybernetics 91(6), 396–407, 2004.

II. Field Neuroscience (Real-world Environments × Evaluation)

Research that extends laboratory methods to conditions closer to real-world settings, linking psychological evaluation with physiological measurement in naturalistic environments. This section also includes peer-reviewed outcomes from collaborative studies with society and industry.

2024: [Representative Paper]
Tsuyoshi Okamoto, Taisuke Nakashima, Kurniawan Eka Permana, Zennifa Fadilla, Yuichiro Watanabe, Shinji Yasunari, Jun Nagano, Noboru Fujimoto, Kuniyoshi Shimizu*: Electrophysiological effects of Japanese cedarwood on sleep quality in humans. Journal of Wood Science 70, 36, 2024.
2023: Taisuke Nakashima, Minkai Sun, Akiyoshi Honden, Yuri Yoshimura, Toshinori Nakagawa, Hiroya Ishikawa, Jun Nagano, Yuki Yamada, Tsuyoshi Okamoto, Yuichiro Watanabe, Shinji Yasunari, Koichiro Ohnuki, Noboru Fujimoto, Kuniyoshi Shimizu*: Effects of volatile sesquiterpenes from Japanese cedarwood on visual processing in the human brain: an event-related potential study. Journal of Wood Science 69, 15, 2023.
2022: Kaori Tamura, Sayaka Matsumoto, Yu Hsuan Tseng, Takayuki Kobayashi, Jun’ichi Miwa, Ken’ichi Miyazawa, Toyotaka Hirao, Soichiro Matsumoto, Seiji Hiramatsu, Hiroyuki Otake, Tsuyoshi Okamoto*: Physiological comfort evaluation under different airflow directions in a heating environment. Journal of Physiological Anthropology 41, 16, 2022.
2021: [Representative Paper]
Kaori Tamura, Sayaka Matsumoto, Yu Hsuan Tseng, Takayuki Kobayashi, Jun’ichi Miwa, Ken’ichi Miyazawa, Toyotaka Hirao, Soichiro Matsumoto, Seiji Hiramatsu, Hiroyuki Otake, Tsuyoshi Okamoto*: Physiological and subjective comfort evaluation under different airflow directions in a cooling environment. PLOS ONE 16, e0249235, 2021.
2020: Minkai Sun, Taisuke Nakashima, Yuri Yoshimura, Akiyoshi Honden, Toshinori Nakagawa, Hiromi Saijo, Yuichiro Watanabe, Tsuyoshi Ajimi, Shinji Yasunari, Yuki Yamada, Jun Nagano, Tsuyoshi Okamoto, Hiroya Ishikawa, Koichiro Ohnuki, Noboru Fujimoto, Kuniyoshi Shimizu: Effects and interaction of different interior material treatment and personal preference on psychological and physiological responses in living environment. Journal of Wood Science 66, 63, 2020.
2017: [Representative Paper]
Tsuyoshi Okamoto*, Kaori Tamura, Naoyuki Miyamoto, Shogo Tanaka, Takaharu Futaeda: Physiological activity in calm thermal indoor environments. Scientific Reports 7, 11519, 2017.
2012: E. Matsubara, K. Shimizu, M. Fukagawa, Y. Ishizi, C. Kakoi, T. Hatayama, J. Nagano, Tsuyoshi Okamoto, K. Ohnuki, R. Kondo: Volatiles emitted from the roots of Vetiveria zizanioides suppress the decline in attention during a visual display terminal task. Biomedical Research 33(5), 299–308, 2012.
2011: Eri Matsubara, Mio Fukagawa, Tsuyoshi Okamoto, Atsuko Fukuda, Chikako Hayashi, Koichiro Ohnuki, Kuniyoshi Shimizu, Ryuichiro Kondo: (−)-Bornyl acetate induces autonomic relaxation and reduces arousal level after visual display terminal work without any influences of task performance in low-dose condition. Biomedical Research 32(2), 151–157, 2011.; Eri Matsubara, Mio Fukagawa, Tsuyoshi Okamoto, Koichiro Ohnuki, Kuniyoshi Shimizu, Ryuichiro Kondo: The essential oil of Abies sibirica (Pinaceae) reduces arousal levels after visual display terminal work. Flavour and Fragrance Journal 26(3), 204–210, 2011.; Eri Matsubara, Mio Fukagawa, Tsuyoshi Okamoto, Atsuko Fukuda, Chikako Hayashi, Koichiro Ohnuki, Kuniyoshi Shimizu, Ryuichiro Kondo: Volatiles emitted from the leaves of Laurus nobilis L. improve vigilance performance in visual discrimination task. Biomedical Research 32(1), 19–28, 2011.

III. Interventions and Plasticity (e.g., Neurofeedback)

Intervention-based research that goes beyond measurement, including approaches such as neurofeedback to modulate neural activity. The aim is to investigate mechanisms of plasticity and assess pathways toward real-world applications.

2021: [Representative Paper]
Yu-Hsuan Tseng, Kaori Tamura, Tsuyoshi Okamoto*: Neurofeedback training improves episodic and semantic long-term memory performance. Scientific Reports 11, 17274, 2021.

IV. Toward Future-Oriented Integration (Future Brain Science / Future Design)

Research expanding from basic functions such as sensation, affect, and preference formation to the neural basis of value creation and decision-making. This provides a foundation for integrating Future Design perspectives into Future Brain Science.

2025: [Representative Paper]
Hongjia Li, Siyao Li, Kenji Matsuo, Tsuyoshi Okamoto*: Brain activity during a cognitive task after consuming food of varying palatability. Frontiers in Psychology 16, 1522812, 2025.
2023: [Representative Paper]
Kaori Tamura*, Tsuyoshi Okamoto: Odor descriptive ratings can predict some odor-color associations in different color features of hue or lightness. PeerJ 11, e15251, 2023.
2018: [Representative Paper]
Kaori Tamura*, Masayuki Hamakawa, Tsuyoshi Okamoto*: Olfactory modulation of colour working memory: How does citrus-like smell influence the memory of orange colour? PLoS ONE 13(9), e0203876, 2018.; Masayuki Hamakawa, Tsuyoshi Okamoto*: The effect of different emotional states on olfactory perception: A preliminary study. Flavour and Fragrance Journal 33, 420–427, 2018.

First published: August 13, 2014.
Major revision: February 19, 2026.
Last updated: April 17, 2026.